Catherine Kaczorowski is quoted in this article that discusses genetic resilience found in a person predisposed to early-onset dementia could lead to new treatments.
As a recent recipient of the Alzheimer’s Association Research Fellowship grant, Singh intends to expand upon his interest in memory formation with the goal of finding practical ways to preserve the brain’s function in Alzheimer’s Disease (AD).
The three-year award will help Singh to investigate the mechanisms of Apoe, a gene with variants known to make some individuals more or less resilient to cognitive decline in AD.
From forestry to neuroscience, Andrew Ouellette’s proclivity for science has earned him a place in the lab. Now, he is helping to discover new connections between life-long dietary restriction and the loss of cognitive function.
It’s logical to think that preventing or reducing the neuronal protein accumulations associated with Alzheimer’s disease (AD)—specifically beta-amyloid plaques and tau tangles—would be an effective therapeutic strategy. Yet to date, efforts in this area, mostly focusing on reducing amyloid, have yielded very little or no benefit.
Kaczorowski of JAX to launch study of genetic factors involved in sleep disturbances in patients with Alzheimer’s disease and other dementias.
Tracking down genes that confer resistance to Huntington’s could lead to new treatment approaches for a devastating neurodegenerative disorder, and brain aging itself.
A conversation with Brianna Gurdon, Summer Student Class of 2018 and Ph.D. candidate in JAX’s Kaczorowski lab.