Publications

Dr. Kaczorowski's publications on Michigan Research Experts

Dr. Kaczorowski's Bibliography on NIH NCBI

Recommended Publications

Harnessing Genetic Complexity to Enhance Translatability of Alzheimer's Disease Mouse Models: A Path toward Precision Medicine

Neuner, S. M., Heuer, S. E., Huentelman, M. J., O'Connell, K. M. S., & Kaczorowski, C. C. (2019). Harnessing Genetic Complexity to Enhance Translatability of Alzheimer's Disease Mouse Models: A Path toward Precision Medicine. Neuron, 101(3), 399–411.e5. https://doi.org/10.1016/j.neuron.2018.11.040

In the news:

Effects of Species-Specific Genetics on Alzheimer’s Mouse Models

In this issue of Neuron, Neuner et al. (2019) report the generation of Alzheimer’s disease (AD) transgenic mouse models on a panel of 28 background strains, showing marked background-dependent phenotypic variability. These findings imply that analogous variation in human AD phenotypes may be due, at least in part, to subtle effects of genetic background.

Neuron Previews, Effects of Species-Specific Genetics on Alzheimer’s Mouse Models 02/06/2019

Translational approaches to understanding resilience to Alzheimer's disease

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Neuner, S. M., Telpoukhovskaia, M., Menon, V., O'Connell, K. M. S., Hohman, T. J., & Kaczorowski, C. C. (2022). Translational approaches to understanding resilience to Alzheimer's disease. Trends in neurosciences, 45(5), 369–383. https://doi.org/10.1016/j.tins.2022.02.005

Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice

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Heuer, S. E., Neuner, S. M., Hadad, N., O'Connell, K. M. S., Williams, R. W., Philip, V. M., Gaiteri, C., & Kaczorowski, C. C. (2020). Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice. Learning & memory (Cold Spring Harbor, N.Y.), 27(9), 355–371. https://doi.org/10.1101/lm.051839.120

Gene-by-environment interactions in Alzheimer’s disease and Parkinson’s disease

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Dunn, A. R., O'Connell, K. M. S., & Kaczorowski, C. C. (2019). Gene-by-environment interactions in Alzheimer's disease and Parkinson's disease. Neuroscience and biobehavioral reviews, 103, 73–80. https://doi.org/10.1016/j.neubiorev.2019.06.018

Life-long dietary restrictions have negligible or damaging effects on late-life cognitive performance: A key role for genetics in outcomes

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Ouellette, A. R., Hadad, N., Deighan, A., Robinson, L., O'Connell, K., Freund, A., Churchill, G. A., & Kaczorowski, C. C. (2022). Life-long dietary restrictions have negligible or damaging effects on late-life cognitive performance: A key role for genetics in outcomes. Neurobiology of aging, 118, 108–116. https://doi.org/10.1016/j.neurobiolaging.2022.07.004

Detecting the effect of genetic diversity on brain composition in an Alzheimer's disease mouse model

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Gurdon, B., Yates, S. C., Csucs, G., Groeneboom, N. E., Hadad, N., Telpoukhovskaia, M., Ouellette, A., Ouellette, T., O'Connell, K., Singh, S., Murdy, T., Merchant, E., Bjerke, I., Kleven, H., Schlegel, U., Leergaard, T. B., Puchades, M. A., Bjaalie, J. G., & Kaczorowski, C. C. (2023). Detecting the effect of genetic diversity on brain composition in an Alzheimer's disease mouse model. bioRxiv : the preprint server for biology, 2023.02.27.530226. https://doi.org/10.1101/2023.02.27.530226

Conserved cell-type specific signature of resilience to Alzheimer’s disease nominates role for excitatory cortical neurons

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Telpoukhovskaia, M., Hadad, N., Gurdon, B., Dai, M., Ouellette, A.R., Neuner, S., Dunn, A.R., Hansen, S.L., Wu, Y., Dumitrescu, L., O'Connell, K.M., Dammer, E.B., Seyfried, N.T., Muzumdar, S., Gillis, J., Robson, P., Zhang, J., Hohman, T.J., Philip, V.M., Menon, V. and Kaczorowski, C.C. (2022), Conserved cell-type specific signature of resilience to Alzheimer’s disease nominates role for excitatory cortical neurons. Alzheimer's Dement., 18: e069370. https://doi.org/10.1002/alz.069370

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