Stephanie Boas

Research Fellow

sboas@umich.edu

Disentangling cell-type-specific etiological contributors is crucial for successful development of targeted therapeutic strategies and translational animal models of age-linked neurodegenerative diseases (e.g. Alzheimer’s, Huntington’s, Parkinson’s). While advances in sequencing technologies and computational approaches have been instrumental in the genomic mapping of complex traits and identification of disease-associated loci, it is often unclear how, or in what cell type(s), genomic variation influences complex disease outcomes. My research interests focus on integrating systems genetics tools, cell-type-specific molecular techniques, and disease-relevant behavioral assays in rodents to define cell-type-specific pathogenic mechanisms across neurodegenerative diseases.